MultiSal® Ceretin®

Retinol, peptide, vitamin C and ALA in one controlled-release anti-aging powder.

ReleaseMoisture · Sweat · Wet lips
FormatPowder
Shelf life24 months

See the data3 figures from lab and in-use testing

FDA-registered facility
GMP manufactured
Made in New Jersey

What it does

Why Ceretin®.

01
Four active ingredients, one powder
Retinol, palmitoyl tripeptide-5, vitamin C and alpha lipoic acid in a single MultiSal® microsphere system.
02
Gentler retinol delivery
Gradual release helps minimize irritation while supporting smoother, firmer-looking skin.
03
Barrier and hydration
Tested at 5% and 10% in a cream base, it improved barrier function and raised skin hydration up to 33%.
04
Easy in water-free bases
A free-flowing powder that incorporates into water-free and traditional skin care.

How it works · MultiSal®

Protected in the jar. Released on use.

A free-flowing, double-encapsulated powder that protects sensitive and volatile active ingredients and releases them on contact with moisture.

ProtectedCeretin® is double encapsulated: SalSphere® units inside a larger microsphere, shielded from the rest of your formula.
TriggeredMoisture from water, sweat or wet lips opens the outer layer, not the jar or the shelf.
ReleasedThe active ingredient is released at the moment of use, at a pace set by the outer layer.

Best inCreamSerumWater-free formulas

See how MultiSal® is built

The evidence

Measured, not promised.

Results from Salvona lab and in-use testing. Select a figure to enlarge it.

TEWL by Ceretin dosage
Sample	10% MultiSal® Ceretin in NCB	5% MultiSal® Ceretin in NCB	Bare skin
Transepidermal water loss	4.38	4.65	17.93

Fig. 1TEWL by Ceretin dosageTransepidermal water loss of bare skin versus skin treated with 5% or 10% MultiSal® Ceretin in NCB. TEWL dropped from 17.93 g/h/m² on bare skin to 4.65 and 4.38 g/h/m².

Skin hydration by Ceretin dosage
Sample	10% MultiSal® Ceretin in NCB	5% MultiSal® Ceretin in NCB	Bare skin
Skin hydration	47.47	44.8	35.63

Fig. 2Skin hydration by Ceretin dosageSkin hydration level of bare skin versus skin treated with 5% or 10% MultiSal® Ceretin in NCB. Hydration rose from 35.63 on bare skin to 44.80 and 47.47.

Powder appearance and microscopy — (A) MultiSal® Ceretin powder, (B) scanning electron microscopy of MultiSal® Ceretin, (C) MultiSal® Ceretin in glycerin at 100× magnification. — Fig. 3Powder appearance and microscopy(A) MultiSal® Ceretin powder, (B) scanning electron microscopy of MultiSal® Ceretin, (C) MultiSal® Ceretin in glycerin at 100× magnification.

For formulators

The spec sheet.

Product code: 9098-06
Platform: MultiSal®
Release trigger: Moisture · Sweat · Wet lips
Appearance: Free flowing powder
Color: Off-White to pale yellow
Use level: 5–10% (as tested in a cream base)
Shelf life: 24 months
INCI: Palmitoyl Tripeptide-5 • Ascorbic Acid • Hyaluronic Acid • Thioctic Acid • Retinol • Aloe Barbadensis Leaf Juice • Butyrospermum Parkii (Shea) Butter • Sodium Starch Octenylsuccinate • Citric Acid • Lactic Acid • Glycerin • Polysorbate 20 • Hydrated Silica

Full product description

MultiSal® Ceretin® is a groundbreaking micro-encapsulation system designed to elevate the performance, stability, and delivery of powerful anti-aging ingredients, including retinol, peptides, vitamin C, and alpha lipoic acid (ALA). This innovative technology not only enhances the potency of these active ingredients but also minimizes irritation while supporting the skin's barrier function, delivering smoother, firmer, and more hydrated skin with long-lasting results.

The core-shell structure of MultiSal® Ceretin® microspheres provides a dual-action mechanism. The hydrophobic core, composed of alpha lipoic acid, natural wax, and aloe vera, retains and delivers functional ingredients, while the polysaccharide-based shell protects these ingredients from environmental degradation and ensures a controlled release. Upon application, the microspheres break down to release submicron spheres for immediate benefits, while ALA facilitates the sustained delivery of retinol to deeper skin layers. This gradual release reduces irritation and maximizes efficacy, offering comprehensive anti-aging effects.

Incorporating MultiSal® Ceretin® into formulations has shown remarkable results in clinical testing. When used in a natural cream base at 5% and 10% concentrations, it demonstrated a 400% improvement in skin barrier function by reducing trans-epidermal water loss (TEWL) and retaining moisture. Additionally, hydration levels in the stratum corneum increased by up to 33%, showcasing its ability to promote healthier, more youthful-looking skin.

The technology’s active ingredients offer targeted benefits: retinol for improved texture and reduced fine lines, palmitoyl tripeptide-5 for collagen stimulation, vitamin C for brightening and antioxidant protection, hyaluronic acid for hydration and plumpness, and aloe vera for soothing and moisturizing. The microsphere powder format ensures easy incorporation into water-free and traditional skincare products, making it versatile for a wide range of formulations.

MultiSal® Ceretin® provides an all-in-one solution for anti-aging, hydration, and skin barrier repair, making it a transformative addition to any skincare regimen or product development.

	9098-06
INCI	Palmitoyl Tripeptide-5, Ascorbic Acid, Hyaluronic Acid, Thioctic Acid, Retinol, Aloe Barbadensis Leaf Juice, Butyrospermum Parkii (Shea) Butter, Sodium Starch Octenylsuccinate, Citric Acid, Lactic Acid, Glycerin, Polysorbate 20, Hydrated Silica

Hover over any ingredient or claim to see details.

Questions

Asked by formulators.

How does the release work?

On application the microspheres break down to release submicron spheres for immediate benefits, while alpha lipoic acid supports sustained retinol delivery to reduce irritation.

What use level was tested?

MultiSal® Ceretin® was tested at 5% and 10% in a natural cream base.

Can it go into anhydrous products?

Yes. The microsphere powder is designed for easy incorporation into water-free and traditional skin care products.